This is basically a 4:3 polyrhythm. You have four chords being evenly spaced across three beats. After every third beat the polyrhythm starts over again. The fourth bar is just something to break away from the polyrhythm pattern being repeated over and over.
Most people struggle a LOT when they learn how to play this, so take your time and break this thing down into as many small pieces as needed so you can better understand what is happening. Good luck!
Here is the Guitar Pro 6 tab for this lesson:
John Taylor - guitar and bass instructor for Mile High Shred.